I don't personally have a reef tank, but if I did, it would exclusively be filled with this Cleaner Shrimp as I hate cleaning fish tanks as much as toilet bowls. While I can pay someone to clean my toilet bowls, my tank is not big enough to warrant out-sourcing that job. Luckily, the wife is pretty good at it now that we have those smaller frankenfish, we she shouldn't need to clean it as much.